副研究员/硕士生导师/澳门大学博士/美国国立卫生院NCI访问学者
研究方向：内脏痛的免疫调节机制与神经分子机制；结肠炎的分子靶点与机制。
联系方式：sailing198562@ntu.edu.cn
个人简介：
从事免疫学方向的研究十余年。近三年来在Science子刊Science Advances、Cellular Oncology, International Immunopharmacology, Frontiers in immunology等国际权威期刊发表SCI论文数篇。主持国家自然科学基金项目1项，南通市自然科学基金项目1项，参与完成5项澳门重大科研项目。担任Cancer Innovation 杂志的青年编委和科学编辑，同时担任Frontiers in immunology杂志的审稿编辑。在World journal of gastrology, Cancer innovation, Exploratory Research and Hypothesis in Medicine, Life research等国际杂志担任审稿专家。
近三年第一作者/通讯作者代表性论文
1. Tianzhen He, De Yang, Xiao-Qing Li, Mengmeng Jiang, Md Sahidul Islam, Shaokui Chen, Yibo Chen, Yang Yang, Chon-kit Chou, Anna Trivett, Joost J. Oppenheim, and Xin Chen. Inhibition of two pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+ Foxp3+ regulatory T cells. Science Advances, 2020; 6, eaba6584 (IF: 14.136, SCI 一区,Nature Index)
2. Tianzhen He, Yibo Chen, De Yang, Md Sahidul Islam, Chon-Kit Chou, Jiarui Liu, Joost J Oppenheim, Xin Chen. TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4+ Foxp3+ regulatory T cells. Cellular Oncology, 2023, 46(1):167-177. （IF: 6.73, SCI 一区）
3. Tianzhen He*, Yi Zhao, Peng Zhao, Liwen Zhao, Jaffry Zakaria, Ke Wang. Signaling pathway(s) of TNFR2 required for the immunoregulatory effect of CD4+ Foxp3+ regulatory T cells. International Immunopharmacology. 2022, 108: 108823. (IF: 5.67 , SCI 二区)
4. Liwen Zhao, Siyu Ye, Shengnan Jing, Yong-jing Gao, Tianzhen He*. Targeting TRIP13 for overcoming anticancer drug resistance. Oncology Reports. 2023, 50(5): 202. doi: 10.3892/or.2023.8639. (IF: 4.2, SCI 三区)
5. Tianzhen He*, Yulian Zhang, Xueyu Li, Caihong Liu, Guanqun Zhu, Xinbao Yin, Zongliang Zhang, Kai Zhao, Zhenlin Wang, Peng Zhao, and Ke Wang. Collective Analysis of the expression and Prognosis for LEM-Domain Proteins in Prostate Cancer. World Journal of Surgical Oncology. 2022, 20(1):174 (IF: 2.477, SCI 三区)
6. Tianzhen He*, Kai Wang, Peng Zhao, Guanqun Zhu, Xinbao Yin, Yulian Zhang, Zongliang Zhang, Kai Zhao, Zhenlin Wang and Ke Wang. Integrative computational approach identifies immune-relevant biomarkers in ulcerative colitis. FEBS Open Biol. 2022, 12: 500-51. (IF: 2.693, SCI 四区)