周国坤,籍贯江苏淮安,助理研究员,本科毕业于上海
大学,2015-2017年继续在上海大学生命科学学院学习,
2017-2019年期间在美国南阿拉巴马大学查向明教授实验室进行2年的学习和科研工作,2020年获上海大学生物信息与系统生物学博士学位。2021年3月进入南通大学特种医学研究院工作。
研究方向:G蛋白偶联受体与疼痛和瘙痒
发表文章:
1. Guokun Zhou, Xiang-ming Zha. GPR68 Contributes to Persistent Acidosis-Induced Activation of AGC Kinases and Tyrosine Phosphorylation in Organotypic Hippocampal Slices. Front Neurosci. 2021 May 25;15:692217.
2. Guokun Zhou*,Tao Wang*, Xiang-ming Zha. RNA-Seq analysis of knocking out the neuroprotective proton-sensitive GPR68 on basal and acute ischemia-induced transcriptome changes and signaling in mouse brain. FASEB J. 2021 Apr;35(4):e21461.
3. Tao Wang* Guokun Zhou* Mindi He, Yuanyuan Xu, W.G. Rusyniak, Yan Xu, Yonghua Ji, Roger P. Simon, Zhi-Gang Xiong, Xiang-ming Zha. GPR68 is a neuroprotective proton receptor in brain ischemia. Stroke 2020 Dec;51(12). (* Co-first author).
4.Guokun Zhou*, Jiping Wu*, Chenchen Xia, Supeng Liu, Feng Jiang, Zhirui Liu, You Zhou, Yonghua Ji. Identifying the toxins in hornet (Vespa basalis) venom that induce rat pain responses. Toxicon. 179:33-41(2020). (* Co-first author)
5.Guokun Zhou*, Yunlu Jiao*, You Zhou, Shichao Qin, Jie Tao, Feng Jiang, Zhi-Yong Tan & Yong-Hua Ji. Up-Regulation of Akt and Nav1.8 in BmK I-Induced Pain. Neurosci. Bull. 34, 539–542 (2018). (* Co-first author)
6. Shichao Qin, Feng Jiang, You Zhou, Guokun Zhou, Pin Ye, Yonghua Ji. Local knockdown of Nav1.6 relieves pain behaviors induced by BmK I, Acta Biochimica et Biophysica Sinica, 2017 Aug 1;49(8):713-721.