吴小波

发布者:翁凌燕发布时间:2021-12-12浏览次数:2586


 

 吴小波,重庆人,生物物理学博士,副研究员,硕士生导师。江苏省第九批科技副总2006年至2012年在陕西师范大学神经生物学和生物物理学专业学习,获博士学位。同年进入南通大学航海医学研究所工作,主要从事慢性疼痛和瘙痒的神经环路和细胞分子机制研究。2017年至2019年在美国纽约州立大学上州医科大学精神与行为学系从事博士后研究。先后发表SCI论文20余篇,包括Neuropsychopharmacology, Neuroscience Bulletin, Journal of Neuroscience等国际权威期刊。主持国家自然科学基金项目2项,江苏省高校自然科学基金面上项目1项,参与完成10余项国家级科研项目;并先后主持完成多项企业合作项目。同时担任Pharmacological ResearchInternational Journal of CancerJournal of Pain; Journal of Neurochemistry; Brain, Behavior and Immunity等国际SCI杂志审稿专家;国家自然科学基金通讯评审专家。

 

研究方向:疼痛和痒觉的神经环路;疼痛抑郁共病的细胞分子机制;新型神经电刺激器的研发。

 

联系方式xbwu1983@ntu.edu.cn

 

近五年代表性论著(第一或通讯作者):

1.        Wu XB*, Zhu Q, Gao YJ*CCL2/CCR2 contributes to the altered excitatory-inhibitory synaptic balance in the nucleus accumbens shell following peripheral nerve injury-induced neuropathic pain. Neuroscience Bulletin, 2021, 37(7): 921-933.

2.        Wu XB, He LN, Jiang BC, Wang X, Lu Y, Gao YJ*. Increased CXCL13 and CXCR5 in anterior cingulate cortex contributes to neuropathic pain-related conditioned place aversion. Neuroscience Bulletin, 2019, 35(4): 613-623.

3.        Wu XB, Jing PB, Zhang ZJ, Cao DL, Gao MH, Jiang BC, Gao YJ*. Chemokine receptor CCR2 contributes to neuropathic pain and the associated depression via increasing NR2B-mediated currents in both D1 and D2 dopamine receptor-containing medium spiny neurons in the nucleus accumbens shell. Neuropsychopharmacology, 2018, 43(11): 2320-2330.

4.        Wu XB, He LN, Jiang BC, Shi H, Bai XQ, Zhang WW, Gao YJ*. Spinal CXCL9 and CXCL11 are not involved in neuropathic pain despite an upregulation in the spinal cord following spinal nerve injury. Molecular pain, 2018, 14: 1-12.

5.        Jiang BC#, He LN#Wu XB#Shi H, Zhang WW, Zhang ZJ, Cao DL, Li CH, Gu J, Gao YJ*. Promoted interaction of C/EBP with demethylated Cxcr3 gene promoter contributes to neuropathic pain in mice. Journal of Neuroscience, 2017, 37 (3) 685-700. (co-first)

6.        Zhang Q, Zhu MD, Cao DL, Bai XQ, Gao YJ, Wu XB*.Chemokine CXCL13 activates p38 MAPK in the trigeminal ganglion after infraorbital nerve injury. Inflammation, 2017, 40(3): 762-769.(通讯作者)

7.        Wu XB, Cao DL, Zhang X, Jiang BC, Zhao LX, Qian B, Gao YJ*. CXCL13/CXCR5 enhances sodium channel Nav1.8 current density via p38 MAP kinase in primary sensory neurons following inflammatory pain. Scientific Reports, 2016, 6: 34836.

8.        Cao DL, Qian B, Zhang ZJ, Gao YJ, Wu XB*. Chemokine receptor CXCR2 in dorsal root ganglion contributes to the maintenance of inflammatory pain. Brain Research Bulletin, 2016, 127: 219-225.(通讯作者)

9.        Wu XB, Liang B, Gao YJ*. The increase of intrinsic excitability of layer V pyramidal cells in the prelimbic medial prefrontal cortex of adult mice after peripheral inflammation.  Neuroscience Letters, 2016, 611: 40-45.