王雪婷

发布者:翁凌燕发布时间:2021-12-11浏览次数:4507

个人简介:王雪婷,副研究员,生理学博士。2009年毕业于南京大学生命科学学院动物学专业,2014年获南京大学生理学博士学位。2019年赴美国康奈尔大学威尔康奈尔医学院访学。主要研究血液低氧与环境低氧对机体的损伤机制及干预。主持国家自然科学基金项目2项,江苏省高校自然科学基金面上项目和南通市基础研究计划青年专项,参与国家自然科学基金项目6项。申请发明专利8项,其中授权发明专利3项目。参与编写《航海医学》教材,主持研究生思政示范课程1项。在SCI收录期刊上发表论文20余篇,包括Science Translational Medicine, Journal of Neuroinflammation, Alzheimer’s Research and Therapy, Journal of Molecular Cell Biology等高水平期刊。主目前担任江苏省生物化学与分子生物学青年委员职务,担任Neural Regeneration Research, Science of the Total Environment, Pharmaceuticals等期刊审稿专家。


近年研究方向:高原脑病的发病机制;间歇性低氧训练对神经退行性疾病的保护机制


联系方式:wangxueting@ntu.edu.cn


近年来代表作:(#共同一作,*通讯作者)

(1) Xueting Wang#, Yuqi Xie#, Xiaoyang Fan, Xiaomei Wu, Dan Wang, Li Zhu*. Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease. Alzheimers Research & Therapy. 2024 Jun 3;16(1):121 (SCI 1区)

(2) Wenyu Ni, Yun Niu, Sitong Cao, Chunsun Fan, Jian Fan, Li Zhu*, Xueting Wang*. Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signaling. Journal of Neuroinflammation. 2024 Jul 2;21(1):166.(SCI 1区)

(3) Xueting Wang#, Yuqi Xie#, Guijuan Chen, Yapeng Lu, Dan Wang, Li Zhu. Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease. Journal of Neuroinflammation. 2023 Oct 20;20(1):240(SCI 1区)

(4) 第一作者: Xueting Wang, Guijuan Chen, Baolan Wan, Zhangji Dong, Yan Xue, Qianqian Luo, Dan Wang, Yapeng Lu, Li Zhu*. NRF1-mediated microglial activation triggers high-altitude cerebral edema. Journal of Molecular Cell Biology, 2022, 14(5), mjac036(SCI 1区)

(5) Xueting Wang, Linlin Huang, Shan Jiang, Kang Cheng, Dan Wang, Qianqian Luo, Xiaomei Wu, Li Zhu*. Testosterone attenuates pulmonary epithelial inflammation in male rats of COPD model through preventing NRF1-derived NF-kB signaling, Journal of Molecular Cell Biology, 2021, 13(2), 128–140(SCI 1区)

(6) Mengmeng Long#, Xuemeng Liu#, Xu Huang, Min Lu, Xiaomei Wu, Lingyan Weng, Qiuping Chen, Xueting Wang*, Li Zhu*, Zhongping Chen*. Alendronate-functionalized hypoxia-responsive polymeric micelles for targeted therapy of bone metastatic prostate cancer, Journal of Controlled Release. 2021, 334: 303–317.(SCI 1区)

(7) Faten A Sayed, Lay Kodama, Li Fan, Gillian K Carling, Joe C Udeochu, David Le, Qingyun Li, Lu Zhou, Man Ying Wong, Rose Horowitz, Pearly Ye, Hansruedi Mathys, Minghui Wang, Xiang Niu, Linas Mazutis, Xueqiao Jiang, Xueting Wang, Fuying Gao, Matthew Brendel, Maria Telpoukhovskaia, Tara E Tracy, Georgia Frost, Yungui Zhou, Yaqiao Li, Yue Qiu, Zuolin; Yu, Guoqiang Cheng, John Hardy, Giovanni Coppola, Fei Wang, Michael A DeTure, Bin Zhang, Lei Xie, John Q Trajnowski, Virginia MY Lee, Shiaoching Gong, Subhash C Sinha, Dennis W Dickson, Wenjie Luo, Li Gan*. AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation. Science Translational Medicine , 2021, 13 (622) , (Nature Index)