江苏溧阳人。2010年毕业于东南大学化学化工学院,材料物理与化学专业博士,现为南通大学副研究员,硕士生导师。研究方向为纳米药剂学,主要以纳米材料(脂质体、聚合物)为载体实现药物对一些恶性疾病(如肿瘤)的靶向和药物在病灶区域的控制释放,最终提高传统药物的治疗作用。主持国家自然科学基金1项,市厅级基金多项;近三年发表SCI一区论文多篇。
代表性课题和文章:
低氧靶向控释磁性聚合物药物载体的构建及作用机制研究(81401506),国家自然科学基金,2015.1-2017.12,项目负责人
1. Mengmeng Long, Xuemeng Liu, Xu Huang, Min Lu, Xiaomei Wu, Lingyan Weng, Qiuping Chen, Xueting Wang, Li Zhu, Zhongping Chen*, Alendronate-functionalized hypoxia-responsive polymeric micelles for targeted therapy of bone metastatic prostate cancer. Journal of Controlled Release 2021 (334) 303 (IF=9.7 中科院一区)
2. Mengmeng Long, Ailing Lu, Min Lu, Lingyan Weng, Qiuping Chen, Li Zhu, Zhongping Chen*, Azo-inserted responsive hybrid liposomes for hypoxia-specific drug delivery. Acta Biomaterialia 2020 (115) 343(IF=8.9 中科院一区)
3. Mingxiang Cao, Mengmeng Long, Qiuping Chen, Yapeng Lu, Qianqian Luo, Yue Zhao, Ailing Lu, Cunwang Ge, Li Zhu, Zhongping Chen*, Development of β-elemene and cisplatin co-loaded liposomes for effective lung cancer therapy and evaluation in patient-derived tumor xenografts. Pharmaceutical research 2019 (36) 1
4. Yi Li, Ailing Lu, Mengmeng Long, Lei Cui, Zhongping Chen*, Li Zhu, Nitroimidazole derivative incorporated liposomes for hypoxia-triggered drug delivery and enhanced therapeutic efficacy in patient-derived tumor xenografts, Acta Biomaterialia 2019 (83) 334 (IF=8.9 中科院一区)
5. Fangfang Wang, Lei Chen, Rui Zhang, Zhongping Chen*, Li Zhu, RGD peptide conjugated liposomal drug delivery system for enhance therapeutic efficacy in treating bone metastasis from prostate cancer. Journal of Controlled Release 2014 (196) 222 (IF=9.7 中科院一区)