吴小波

发布者:系统管理员发布时间:2016-04-01浏览次数:1


吴小波,生物物理学专业博士,副研究员。200609月至201207月在陕西师范大学神经生物学和生物物理学专业学习,获理学博士学位。同年进入南通大学航海医学研究所工作,主要从事慢性疼痛和瘙痒的神经环路和细胞机制研究。201708月至201902月在美国纽约州立大学上州医科大学精神与行为学系从事博士后研究。近年来,以第一或通讯作者发表SCI论文10余篇,包括Neuropsychopharmacology,Molecular pain, Journal of Neuroscience等国际权威期刊。先后主持完成国家自然科学基金青年项目1项,江苏省高校自然科学基金面上项目1项,并作为主要成员参与或完成7项国家自然科学基金项目。担任PharmacologicalResearchInternational Journal of CancerSCI杂志审稿人。

研究兴趣:慢性疼痛、瘙痒发生的神经环路和电生理机制;细胞兴奋行及突触可塑的生物物理学机制研究。

代表性论著:

1. Wu XB,Jing PB, Zhang ZJ, Cao DL, Gao MH, Jiang BC, Gao YJ*. Chemokine receptor CCR2

contributes to neuropathic pain and theassociated depression via increasing NR2B-mediated

currents in both D1 and D2 dopaminereceptor-containing medium spiny neurons in the nucleus

accumbens shell. Neuropsychopharmacology,2018, 43(11): 2320-2330. (IF=6.54, JCR 1)

2. Wu XB,He LN, Jiang BC, Shi H, Bai XQ, Zhang WW, Gao YJ*. Spinal CXCL9 and CXCL11

are not involved in neuropathic pain despitean upregulation in the spinal cord following spinal

nerve injury. Molecular pain,2018, 14: 1-12. (IF=3.21, JCR 2)

3. Jiang BC #,He LN #, Wu XB #, Shi H, Zhang WW, Zhang ZJ, CaoDL, Li CH, Gu J, Gao YJ*

Promoted interaction of C/EBP withdemethylated Cxcr3 gene promoter contributes to

neuropathic pain in mice. Journal ofNeuroscience, 2017, 37 (3) 685-700. (IF=5.99, JCR 1)

(co-first)

4. Zhang Q,Zhu MD, Cao DL, Bai XQ, Gao YJ, Wu XB*. Chemokine CXCL13 activates p38

MAPK in the trigeminal ganglion afterinfraorbital nerve injury. Inflammation, 2017, 40(3):

762-769. (IF=2.88, JCR 3)Correspondingauthor

5. Wu XB,Cao DL, Zhang X, Jiang BC, Zhao LX, Qian B, Gao YJ*. CXCL13/CXCR5 enhances

sodium channel Nav1.8 current density via p38MAP kinase in primary sensory neurons

following inflammatory pain. ScientificReports, 2016, 6: 34836. (IF=4.12, JCR 2)

6. Cao DL,Qian B, Zhang ZJ, Gao YJ, Wu XB*. Chemokine receptor CXCR2 in dorsalroot

ganglion contributes to the maintenance ofinflammatory pain. Brain Research Bulletin, 2016,

127: 219-225. (IF=3.44, JCR 3) Corresponding author

7. Wu XB,Liang B, Gao YJ *. The increase of intrinsic excitability of layer V pyramidalcells in

the prelimbic medial prefrontal cortex ofadult mice after peripheral inflammation.

Neuroscience Letters, 2016,611: 40-45. (IF=2.16, JCR 4)

8. Wu XB,Shi MM, Wei CL, Liu YH, Liu ZQ *, Ren W. Effects of morphine withdrawal on the

membrane properties of medium spiny neuronsin the nucleus accumbens shell. Brain Research

Bulletin, 2013, 90:92-99. (IF=3.44, JCR 3)

9. Wu XB,Shi MM, Wei CL, Yang MH, Liu YH, Liu ZQ *, Zhang X, Ren W. Potentiation of

synaptic strength and intrinsic excitabilityin the nucleus accumbens after 10 days of morphine

withdrawal. Journal of NeuroscienceResearch, 2012, 90(6): 1270-1283. (IF=2.66, JCR 3)

10. Wu XB,Mo J, Yang MH, Zheng QH, Gu HG*, Ren W*. Two Different Bifurcation Scenarios

in Neural Firing Rhythms Discovered inBiological Experiments by Adjusting Two Parameters.

Chin. Physic. Lett., 2008, 25:2799 -2802. (SCI, JCR 4)